“Seeking and using the evidence in clinical practice”

Oxford–Thessaloniki Diabetes Forum is a 3-day course for young diabetologists, organised by the Oxford Centre for Diabetes Endocrinology and Metabolism (OCDEM) and the Second Medical Department of the Aristotle University Thessaloniki. Faculty comprises of experts in the field from OCDEM, McMaster University Canada and universities across Greece (Athens, Thessaloniki and Alexandrupoli).

The content focuses on the practice of evidence accumulation, retrieval and establishing appraisal techniques for research and clinical practice in diabetes. This course aims to provide an opportunity for young enthusiastic diabetologists to get a taste of research and clinical practice in Centres of Excellence. Working together, participants will learn how simple evidence-based medicine and research techniques can be applied to improve diabetes care. Research experience is not required.

The course is under the auspices of the Medical School, Aristotle University Thessaloniki, Harris Manchester Medical Academy, Hellenic Diabetes Association and European Association for the Study of Diabetes. The course is supported by an unrestricted educational grant from Novo Nordisk.



DAY 1: Wednesday, 13th May 2015
09:00 - 09:30 Registration & welcome

What is evidence-based medicine / practice?

Speaker: A. Tsapas
09:30 – 10:00

Asking well formulated questions – PICO

Speaker: N. Papanas
10:00 – 10:20

Searching basics – Finding the evidence

Speaker: N. Papanas
10:20 – 10:45
10:45 - 11:15 Coffee / Tea

Rapid critical appraisal

Speaker: D. Goulis
11:15 – 12:00

Study design

Speaker: A. Tatsioni
12:00 – 12:30

Trials, trials, trials

12:30 – 13:30
13:30 - 14:30 Lunch break

Systematic reviews – Metaanalysis – Cochrane

Speaker: M. Trivella
14:30 – 15:15

Taking action – Applying the evidence

Speaker: A. Tatsioni
15:15 – 16:00
16:00 - 16:30 Coffee / Tea

Crash course: 4 in 1

Workshop: D. Goulis, A. Tatsioni, M. Trivella, A. Tsapas
16:30 – 18:30
DAY 2: Thursday, 14th May 2015

Numbers, numbers, numbers

Speaker: D. Matthews
08:45 – 10:00

Stats in small doses

Speaker: J. Levy
10:00 – 10:45
10:45 - 11:15 Coffee / Tea

Hypothesis formulation & project design

Speaker: D. Matthews
11:15 – 11:45
Research project (in silico) - Workshop

Introduction to Workshop and Experimental Scenarios

Speakers: A. Clark, J. Levy
11:45 – 12:00

Data analysis

Speakers: A. Clark, J. Levy, D. Matthews
12:00 – 13:30
13:30 - 14:30 Lunch break

Preparation of abstract & slides

Speakers: A. Clark, J. Levy, D. Matthews
14:30 – 16:00


Speakers: A. Clark, J. Levy, D. Matthews
16:00 – 18:00
DAY 3: Friday, 15th May 2015

Using the literature

Speaker: A. Clark
08:45 – 09:45

Hypoglycaemia in type 2 diabetes – in life and in trials

Speaker: J. Levy
09:45 – 10:30
10:30 - 11:00 Coffee / Tea

Implementing patient preferences and patient important outcomes in diabetes care

Speaker: A. Tsapas
11:00 – 11:30

Preventing diabetes - social science, sense, statistics or stasis?

Speaker: D. Matthews
11:30 – 12:00



Anne Clark

Anne Clark is a Principal Investigator in Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) with a specialty in the structure and function of pancreatic islets in Type 2 diabetes.

In 1987, with the late Professor Robert Turner, her team identified the peptide component of amyloid deposits (islet amyloid polypeptide, amylin) that form in the pancreatic islets in Type 2 diabetes. Her current interests include protein folding and amyloid formation, lipid handling in islets and structure and function of pancreatic islets in health and disease using light and electron microscopy; collaborators include colleagues in UK, Europe, USA, Canada and Australia.

She participates in graduate teaching programmes in UK and Europe, reviews grant applications and manuscripts for scientific journals.


Dimitrios Goulis

Dr. Dimitrios G. Goulis was born in Thessaloniki, Greece. He completed his basic medical training (M.D.) and received his Ph.D. degree from the Aristotle University of Thessaloniki (A.U.Th.). Having a European Union scholarship, he worked for four years at St. Mary’s and Hammersmith Hospitals, London, UK, acquiring the specialty of Endocrinology and Metabolism. During his training in the UK, he worked in the fields of metabolism, reproductive endocrinology and metabolic complications of pregnancy, under the supervision of professors Desmond Johnston, Stephen Franks and Michael de Swiet. In 2004, he was appointed lecturer and in 2009 assistant professor of Reproductive Endocrinology in the First Department of Obstetrics and Gynecology, A.U.Th. (Head: Professor Basil C. Tarlatzis). Dr. Goulis’ main research interests include endocrine complications of pregnancy, Andrology and research methodology. He has published more than 90 full papers in peer-review international journals. Currently he is associate editor of “Human Reproduction” and a member of the executive councils of the European Academy of Andrology and the Hellenic Endocrine Society.


Jonathan Levy

Dr Jonathan Levy is Clinical Director of the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) and is responsible for the delivery of specialist National Health Service diabetes care for Oxfordshire where he is also actively involved in teaching.

He is based in the University of Oxford Nuffield Department of Clinical Medicine and his research interests focus on the pathophysiology and treatment of type 2 diabetes. He is a member of the steering committee of the 4-T (Treat to Target in Type 2 diabetes) trial and a co-author on publications arising from the study. He has published papers on the assessment of β-cell function, insulin resistance in diabetes and on potential treatments for diabetes.


David R. Matthews

David Matthews is Professor of Diabetes Medicine at the University of Oxford, Medical Tutor, at Harris Manchester College, consultant physician and the Chairman of the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), one of the largest combined academic and clinical centres for diabetes and endocrinology in the UK.

His academic research interests include mathematical modelling of insulin resistance. There is a research focus on physiological research into diabetes agents, in particular at the level of the beta-cell involving incretins and sulphonylureas. An ongoing concern about the world pandemic of diabetes resulted in the founding of the Oxford Health Alliance which published its ‘Grand challenges’ in Nature in 2007 (www.3four50.com) and is working towards combating the scourge of the diabetes epidemic in the world. We are establishing an observational link to the Andover Vision project – a UK civic renewal programme.

He is the author of more than 200 publications and is on the editorial boards of several professional journals.


Evangelia Ntzani

Assistant Professor, University of Ioannina, Greece


Nikolaos Papanas

Dr. Nikolaos Papanas was born in Thessaloniki, Greece and studied Medicine at Aristotle University of Thessaloniki. In 2002, he defended his dissertation on the co-existence of peripheral arterial and coronary artery disease in patients with diabetes. Between 2003 and 2008, he worked as Senior Lecturer in Internal Medicine at Democritus University of Thrace, Alexandroupolis, Greece. Since 2008, his current position is Assistant Professor in Internal Medicine at the same university.

He was trained in diabetes and its complications in the Diabetes Centre and the Diabetic Foot Clinic at King’s College Hospital, London, UK. He has published more than 50 papers in peer-reviewed journals. He has also participated with numerous presentations in Greek and European medical congresses and repeatedly been invited reviewer in medical journals.


Marialena Trivella

Lecturer in Systematic Reviews, UK Cochrane Centre, University of Oxford, UK


Apostolos Tsapas

Dr. Apostolos Tsapas was born in Thessaloniki, Greece and studied Medicine at Aristotle University of Thessaloniki. He is currently Assistant Professor of Medicine and Principal Investigator in the Diabetes Clinic at the Second Medical Department of the Aristotle University Thessaloniki in Ippokratio Hospital. He is a Senior Research Fellow in the Medical Academy within Harris Manchester College, Oxford UK. He was trained in diabetes in the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) with Prof. Dr Matthews, with a fellowship from the European Foundation for the Study of Diabetes (Albert Renold Fellowship – EFSD). This was the starting point for the setup of Oxford Thessaloniki Diabetes Forum.

His main research interests focus on research methodology, evidence-based medicine/diabetology, translational research/knowledge translation and physiological studies in diabetes. He is currently studying for an MSc in Evidence-Βased Health Care in the Centre for Evidence-Based Medicine, Oxford UK.


The cooperation between Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) and the Metabolic Diseases Unit, Second Medical Department, Aristotle University Thessaloniki (Assoc Prof Konstantinos Paletas) began in 2007. Starting point was Dr Tsapas’ sabbatical with Prof DR Matthews in OCDEM, supported by an EFSD (European Foundation for the Study of Diabetes – Albert Renold) fellowship. This cooperation was supported both by Prof Maria Raptopoulou – Gigi (Head, Second Medical Department) and Prof Nikolaos Dombros (Dean, Medical School).

Aim is the setup of educational and research links between centres of excellence, to support postgraduate education, and career development of academic personnel.

Oxford – Thessaloniki Forum is the realisation of this link. We do hope that this course, which focuses on the interaction of young diabetologists with experienced researchers, will be successful, and will lead to further common educational and research links.


Oxford-Thessaloniki Diabetes Forum. Sponsored by Novo_Nordisk2

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